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SMILES: NC(=O)CC[C@H](NC(=O)[C@@H]1CC[C@@H]2CC[C@H](NC(=O)\C=C\c3ccc(OP(O)(O)=O)cc3)C(=O)N12)C(=O)NCc1ccccc1

InChI Key: InChIKey=JPWWIKGPDPHWJU-MHRYKNMFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267448   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Signal transducer and activator of transcription 3


(Homo sapiens (Human))		BDBM50267448
PNG
(4-(3-((3S,6S,8aS)-3-((S)-5-amino-1-(benzylamino)-1...)
Show SMILES NC(=O)CC[C@H](NC(=O)[C@@H]1CC[C@@H]2CC[C@H](NC(=O)\C=C\c3ccc(OP(O)(O)=O)cc3)C(=O)N12)C(=O)NCc1ccccc1 |r|
Show InChI InChI=1S/C30H36N5O9P/c31-26(36)16-14-23(28(38)32-18-20-4-2-1-3-5-20)34-29(39)25-15-10-21-9-13-24(30(40)35(21)25)33-27(37)17-8-19-6-11-22(12-7-19)44-45(41,42)43/h1-8,11-12,17,21,23-25H,9-10,13-16,18H2,(H2,31,36)(H,32,38)(H,33,37)(H,34,39)(H2,41,42,43)/b17-8+/t21-,23-,24-,25-/m0/s1
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Similars
Article
PubMed
n/an/a 604n/an/an/an/an/an/a



The University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inhibition of Stat3 (unknown origin) by fluorescence polarization assay

J Med Chem 52: 2429-42 (2009)


Article DOI: 10.1021/jm801491w
BindingDB Entry DOI: 10.7270/Q28C9W4V
More data for this
Ligand-Target Pair