BDBM50267563 3-(6-Chloro-5-methoxy-1-methyl-1H-indol-3-yl)-4-(6-cyclopropylmethoxybenzofuran-3-yl)pyrrole-2,5-dione::CHEMBL490639

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2coc3cc(OCC4CC4)ccc23)c2cc(F)c(Cl)cc12

InChI Key: InChIKey=PSPCPBAGSCATKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50267563 (3-(6-Chloro-5-methoxy-1-methyl-1H-indol-3-yl)-4-(6...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2coc3cc(OCC4CC4)ccc23)c2cc(F)c(Cl)cc12 |t:4| Show InChI InChI=1S/C25H18ClFN2O4/c1-29-9-16(15-7-19(27)18(26)8-20(15)29)22-23(25(31)28-24(22)30)17-11-33-21-6-13(4-5-14(17)21)32-10-12-2-3-12/h4-9,11-12H,2-3,10H2,1H3,(H,28,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by scintillation counting				J Med Chem 52: 1853-63 (2009) Article DOI: 10.1021/jm801317h BindingDB Entry DOI: 10.7270/Q24M94FZ
					More data for this Ligand-Target Pair