BDBM50267888 CHEMBL4104462

SMILES: OP(O)(=O)Oc1ccc(CNC(=O)COc2ccc3cc(ccc3c2)C(=O)Nc2ccc(F)cc2)cc1OP(O)(O)=O

InChI Key: InChIKey=ZKCZWJVLGKHHAV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor STAT5b (STAT5b) (Homo sapiens (Human))	BDBM50267888 (CHEMBL4104462) Show SMILES OP(O)(=O)Oc1ccc(CNC(=O)COc2ccc3cc(ccc3c2)C(=O)Nc2ccc(F)cc2)cc1OP(O)(O)=O Show InChI InChI=1S/C26H23FN2O11P2/c27-20-5-7-21(8-6-20)29-26(31)19-3-2-18-13-22(9-4-17(18)12-19)38-15-25(30)28-14-16-1-10-23(39-41(32,33)34)24(11-16)40-42(35,36)37/h1-13H,14-15H2,(H,28,30)(H,29,31)(H2,32,33,34)(H2,35,36,37)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany. Curated by ChEMBL					Assay Description Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...				Bioorg Med Chem 25: 3871-3882 (2017) Article DOI: 10.1016/j.bmc.2017.05.039 BindingDB Entry DOI: 10.7270/Q26Q20RB
					More data for this Ligand-Target Pair
Transcription factor STAT5a (STAT5a) (Homo sapiens (Human))	BDBM50267888 (CHEMBL4104462) Show SMILES OP(O)(=O)Oc1ccc(CNC(=O)COc2ccc3cc(ccc3c2)C(=O)Nc2ccc(F)cc2)cc1OP(O)(O)=O Show InChI InChI=1S/C26H23FN2O11P2/c27-20-5-7-21(8-6-20)29-26(31)19-3-2-18-13-22(9-4-17(18)12-19)38-15-25(30)28-14-16-1-10-23(39-41(32,33)34)24(11-16)40-42(35,36)37/h1-13H,14-15H2,(H,28,30)(H,29,31)(H2,32,33,34)(H2,35,36,37)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany. Curated by ChEMBL					Assay Description Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5A SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...				Bioorg Med Chem 25: 3871-3882 (2017) Article DOI: 10.1016/j.bmc.2017.05.039 BindingDB Entry DOI: 10.7270/Q26Q20RB
					More data for this Ligand-Target Pair