BDBM50268617 CHEMBL4093367

SMILES: Cn1cc(C2CCN(CC2)C(=O)OC(C)(C)C)c2ncnc(Nc3ccc(cc3F)S(C)(=O)=O)c12

InChI Key: InChIKey=MJPNSSIXNQZYSN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268617   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268617 (CHEMBL4093367) Show SMILES Cn1cc(C2CCN(CC2)C(=O)OC(C)(C)C)c2ncnc(Nc3ccc(cc3F)S(C)(=O)=O)c12 Show InChI InChI=1S/C24H30FN5O4S/c1-24(2,3)34-23(31)30-10-8-15(9-11-30)17-13-29(4)21-20(17)26-14-27-22(21)28-19-7-6-16(12-18(19)25)35(5,32)33/h6-7,12-15H,8-11H2,1-5H3,(H,26,27,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 27: 3249-3253 (2017) Article DOI: 10.1016/j.bmcl.2017.06.034 BindingDB Entry DOI: 10.7270/Q2TB19CJ
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