BDBM50268631 CHEMBL4104336

SMILES: CC(=O)c1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O

InChI Key: InChIKey=NTYGLVPCHNBPKP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268631 (CHEMBL4104336) Show SMILES CC(=O)c1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O Show InChI InChI=1S/C26H26N6O4S/c1-16(33)19-12-27-26(28-13-19)31-8-5-17(6-9-31)21-14-36-24-23(21)29-15-30-25(24)32-10-7-18-11-20(37(2,34)35)3-4-22(18)32/h3-4,11-15,17H,5-10H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 27: 3249-3253 (2017) Article DOI: 10.1016/j.bmcl.2017.06.034 BindingDB Entry DOI: 10.7270/Q2TB19CJ
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