BDBM50268639 CHEMBL4099566

SMILES: CC(C)(C)OC(=O)N1CCC(CC1)n1nnc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12

InChI Key: InChIKey=SCIOWJWEEDMNRR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268639 (CHEMBL4099566) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1nnc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12 Show InChI InChI=1S/C21H26FN7O4S/c1-21(2,3)33-20(30)28-9-7-13(8-10-28)29-19-17(26-27-29)18(23-12-24-19)25-16-6-5-14(11-15(16)22)34(4,31)32/h5-6,11-13H,7-10H2,1-4H3,(H,23,24,25)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in HEK293 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 27: 3249-3253 (2017) Article DOI: 10.1016/j.bmcl.2017.06.034 BindingDB Entry DOI: 10.7270/Q2TB19CJ
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