null

SMILES: OC(=O)C1=C(CCCC1)NC(=O)\C=C\C#Cc1ccc(O)cc1F

InChI Key: InChIKey=RSIXRSXTZVORGJ-XBXARRHUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50268976 (CHEMBL4093990) Show SMILES OC(=O)C1=C(CCCC1)NC(=O)\C=C\C#Cc1ccc(O)cc1F |t:3| Show InChI InChI=1S/C18H16FNO4/c19-15-11-13(21)10-9-12(15)5-1-4-8-17(22)20-16-7-3-2-6-14(16)18(23)24/h4,8-11,21H,2-3,6-7H2,(H,20,22)(H,23,24)/b8-4+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Latvian Institute of Organic Synthesis Curated by ChEMBL					Assay Description Agonist activity at recombinant human HCA2 receptor expressed in Flp-IN HEK cells assessed as reduction in forskolin-stimulated cAMP accumulation mea...				Bioorg Med Chem 25: 4314-4329 (2017) Article DOI: 10.1016/j.bmc.2017.06.028 BindingDB Entry DOI: 10.7270/Q2D22140
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50268976 (CHEMBL4093990) Show SMILES OC(=O)C1=C(CCCC1)NC(=O)\C=C\C#Cc1ccc(O)cc1F |t:3| Show InChI InChI=1S/C18H16FNO4/c19-15-11-13(21)10-9-12(15)5-1-4-8-17(22)20-16-7-3-2-6-14(16)18(23)24/h4,8-11,21H,2-3,6-7H2,(H,20,22)(H,23,24)/b8-4+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	331	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Institute of Organic Synthesis Curated by ChEMBL					Assay Description Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...				Bioorg Med Chem 25: 4314-4329 (2017) Article DOI: 10.1016/j.bmc.2017.06.028 BindingDB Entry DOI: 10.7270/Q2D22140
					More data for this Ligand-Target Pair