BDBM50269705 CHEMBL4102588

SMILES: CN1CCC(CC1)NC(=O)c1cn(C)c(=O)c2[nH]ccc12

InChI Key: InChIKey=ZSADJWPNTYFYBX-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50269705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cat eye syndrome critical region protein 2 (Homo sapiens (Human))	BDBM50269705 (CHEMBL4102588) Show SMILES CN1CCC(CC1)NC(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C15H20N4O2/c1-18-7-4-10(5-8-18)17-14(20)12-9-19(2)15(21)13-11(12)3-6-16-13/h3,6,9-10,16H,4-5,7-8H2,1-2H3,(H,17,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged CECR2 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assay				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Homo sapiens (Human))	BDBM50269705 (CHEMBL4102588) Show SMILES CN1CCC(CC1)NC(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C15H20N4O2/c1-18-7-4-10(5-8-18)17-14(20)12-9-19(2)15(21)13-11(12)3-6-16-13/h3,6,9-10,16H,4-5,7-8H2,1-2H3,(H,17,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD9 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET as...				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50269705 (CHEMBL4102588) Show SMILES CN1CCC(CC1)NC(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C15H20N4O2/c1-18-7-4-10(5-8-18)17-14(20)12-9-19(2)15(21)13-11(12)3-6-16-13/h3,6,9-10,16H,4-5,7-8H2,1-2H3,(H,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD4 bromodomain 2 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins...				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50269705 (CHEMBL4102588) Show SMILES CN1CCC(CC1)NC(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C15H20N4O2/c1-18-7-4-10(5-8-18)17-14(20)12-9-19(2)15(21)13-11(12)3-6-16-13/h3,6,9-10,16H,4-5,7-8H2,1-2H3,(H,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD4 bromodomain 1 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assay				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM50269705 (CHEMBL4102588) Show SMILES CN1CCC(CC1)NC(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C15H20N4O2/c1-18-7-4-10(5-8-18)17-14(20)12-9-19(2)15(21)13-11(12)3-6-16-13/h3,6,9-10,16H,4-5,7-8H2,1-2H3,(H,17,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged TAF1 bromodomain 2 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins...				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair