BDBM50269706 CHEMBL4088418

SMILES: CN(C1CCN(C)CC1)C(=O)c1cn(C)c(=O)c2[nH]ccc12

InChI Key: InChIKey=WSBRDLIMEGQZPA-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50269706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cat eye syndrome critical region protein 2 (Homo sapiens (Human))	BDBM50269706 (CHEMBL4088418) Show SMILES CN(C1CCN(C)CC1)C(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C16H22N4O2/c1-18-8-5-11(6-9-18)20(3)15(21)13-10-19(2)16(22)14-12(13)4-7-17-14/h4,7,10-11,17H,5-6,8-9H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged CECR2 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assay				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Homo sapiens (Human))	BDBM50269706 (CHEMBL4088418) Show SMILES CN(C1CCN(C)CC1)C(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C16H22N4O2/c1-18-8-5-11(6-9-18)20(3)15(21)13-10-19(2)16(22)14-12(13)4-7-17-14/h4,7,10-11,17H,5-6,8-9H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD9 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET as...				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50269706 (CHEMBL4088418) Show SMILES CN(C1CCN(C)CC1)C(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C16H22N4O2/c1-18-8-5-11(6-9-18)20(3)15(21)13-10-19(2)16(22)14-12(13)4-7-17-14/h4,7,10-11,17H,5-6,8-9H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD4 bromodomain 2 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins...				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50269706 (CHEMBL4088418) Show SMILES CN(C1CCN(C)CC1)C(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C16H22N4O2/c1-18-8-5-11(6-9-18)20(3)15(21)13-10-19(2)16(22)14-12(13)4-7-17-14/h4,7,10-11,17H,5-6,8-9H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD4 bromodomain 1 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assay				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM50269706 (CHEMBL4088418) Show SMILES CN(C1CCN(C)CC1)C(=O)c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C16H22N4O2/c1-18-8-5-11(6-9-18)20(3)15(21)13-10-19(2)16(22)14-12(13)4-7-17-14/h4,7,10-11,17H,5-6,8-9H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-FLAG-tagged TAF1 bromodomain 2 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins...				ACS Med Chem Lett 8: 737-741 (2017) Article DOI: 10.1021/acsmedchemlett.7b00132 BindingDB Entry DOI: 10.7270/Q2862JXN
					More data for this Ligand-Target Pair