BDBM50269945 CHEMBL4092221

SMILES: Cl.COc1ccc(\C=C\C2=NN(CCCCN)C(=O)N(Cc3ccc4ccccc4c3)c3ccccc23)cc1

InChI Key: InChIKey=NKZTVWHDNWNDGG-XDJHFCHBSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UTS2R (RAT)	BDBM50269945 (CHEMBL4092221) Show SMILES Cl.COc1ccc(\C=C\C2=NN(CCCCN)C(=O)N(Cc3ccc4ccccc4c3)c3ccccc23)cc1 |t:8| Show InChI InChI=1S/C32H32N4O2/c1-38-28-17-13-24(14-18-28)15-19-30-29-10-4-5-11-31(29)35(32(37)36(34-30)21-7-6-20-33)23-25-12-16-26-8-2-3-9-27(26)22-25/h2-5,8-19,22H,6-7,20-21,23,33H2,1H3/b19-15+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aorta assessed as change in URP-mediated aortic ring contraction by meas...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair
UTS2R (RAT)	BDBM50269945 (CHEMBL4092221) Show SMILES Cl.COc1ccc(\C=C\C2=NN(CCCCN)C(=O)N(Cc3ccc4ccccc4c3)c3ccccc23)cc1 |t:8| Show InChI InChI=1S/C32H32N4O2/c1-38-28-17-13-24(14-18-28)15-19-30-29-10-4-5-11-31(29)35(32(37)36(34-30)21-7-6-20-33)23-25-12-16-26-8-2-3-9-27(26)22-25/h2-5,8-19,22H,6-7,20-21,23,33H2,1H3/b19-15+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aorta assessed as change in human urotensin-2-mediated aortic ring contr...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair