BDBM50270041 4'-Iodo-biphenyl-4-carboxylic acid {1-[(S)-1-(2-diazo-acetyl)-butylcarbamoyl]-3-methyl-butyl}-amide::CHEMBL518284

SMILES: CCC[C@H](NC(=O)C(CC(C)C)NC(=O)c1ccc(cc1)-c1ccc(I)cc1)C(=O)[CH-][N+]#N

InChI Key: InChIKey=VHNVOAVIDBRLFO-HMTLIYDFSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50270041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50270041 (4'-Iodo-biphenyl-4-carboxylic acid {1-[(S)-1-(2-di...) Show SMILES CCC[C@H](NC(=O)C(CC(C)C)NC(=O)c1ccc(cc1)-c1ccc(I)cc1)C(=O)[CH-][N+]#N |r| Show InChI InChI=1S/C25H29IN4O3/c1-4-5-21(23(31)15-28-27)29-25(33)22(14-16(2)3)30-24(32)19-8-6-17(7-9-19)18-10-12-20(26)13-11-18/h6-13,15-16,21-22H,4-5,14H2,1-3H3,(H,29,33)(H,30,32)/t21-,22?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C after 10 mins				J Biol Chem 282: 20836-46 (2007) Article DOI: 10.1074/jbc.M702615200 BindingDB Entry DOI: 10.7270/Q2125TJM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50270041 (4'-Iodo-biphenyl-4-carboxylic acid {1-[(S)-1-(2-di...) Show SMILES CCC[C@H](NC(=O)C(CC(C)C)NC(=O)c1ccc(cc1)-c1ccc(I)cc1)C(=O)[CH-][N+]#N |r| Show InChI InChI=1S/C25H29IN4O3/c1-4-5-21(23(31)15-28-27)29-25(33)22(14-16(2)3)30-24(32)19-8-6-17(7-9-19)18-10-12-20(26)13-11-18/h6-13,15-16,21-22H,4-5,14H2,1-3H3,(H,29,33)(H,30,32)/t21-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin S after 10 mins				J Biol Chem 282: 20836-46 (2007) Article DOI: 10.1074/jbc.M702615200 BindingDB Entry DOI: 10.7270/Q2125TJM
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50270041 (4'-Iodo-biphenyl-4-carboxylic acid {1-[(S)-1-(2-di...) Show SMILES CCC[C@H](NC(=O)C(CC(C)C)NC(=O)c1ccc(cc1)-c1ccc(I)cc1)C(=O)[CH-][N+]#N |r| Show InChI InChI=1S/C25H29IN4O3/c1-4-5-21(23(31)15-28-27)29-25(33)22(14-16(2)3)30-24(32)19-8-6-17(7-9-19)18-10-12-20(26)13-11-18/h6-13,15-16,21-22H,4-5,14H2,1-3H3,(H,29,33)(H,30,32)/t21-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin L after 10 mins				J Biol Chem 282: 20836-46 (2007) Article DOI: 10.1074/jbc.M702615200 BindingDB Entry DOI: 10.7270/Q2125TJM
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50270041 (4'-Iodo-biphenyl-4-carboxylic acid {1-[(S)-1-(2-di...) Show SMILES CCC[C@H](NC(=O)C(CC(C)C)NC(=O)c1ccc(cc1)-c1ccc(I)cc1)C(=O)[CH-][N+]#N |r| Show InChI InChI=1S/C25H29IN4O3/c1-4-5-21(23(31)15-28-27)29-25(33)22(14-16(2)3)30-24(32)19-8-6-17(7-9-19)18-10-12-20(26)13-11-18/h6-13,15-16,21-22H,4-5,14H2,1-3H3,(H,29,33)(H,30,32)/t21-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin B after 10 mins				J Biol Chem 282: 20836-46 (2007) Article DOI: 10.1074/jbc.M702615200 BindingDB Entry DOI: 10.7270/Q2125TJM
					More data for this Ligand-Target Pair