BDBM50270549 CHEMBL503256::P1-((2-benzyl-1,3-dioxolo-4-yl)uridine 5')P3-(5-iodouridine5') triphosphate

SMILES: O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@@H]2OC(Cc3ccccc3)O[C@H]12)n1ccc(=O)[nH]c1=O)n1cc(I)c(=O)[nH]c1=O

InChI Key: InChIKey=QLNLOFBLBCXERM-RLNMLFRGSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyrimidinergic receptor P2Y6 (Homo sapiens (Human))	BDBM50270549 (CHEMBL503256 | P1-((2-benzyl-1,3-dioxolo-4-yl)urid...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@@H]2OC(Cc3ccccc3)O[C@H]12)n1ccc(=O)[nH]c1=O)n1cc(I)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C26H30IN4O20P3/c27-13-9-31(26(37)29-22(13)35)23-19(34)18(33)14(46-23)10-44-52(38,39)50-54(42,43)51-53(40,41)45-11-15-20-21(24(47-15)30-7-6-16(32)28-25(30)36)49-17(48-20)8-12-4-2-1-3-5-12/h1-7,9,14-15,17-21,23-24,33-34H,8,10-11H2,(H,38,39)(H,40,41)(H,42,43)(H,28,32,36)(H,29,35,37)/t14-,15-,17?,18-,19-,20-,21-,23-,24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.49E+3	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...				Bioorg Med Chem 16: 6319-32 (2008) Article DOI: 10.1016/j.bmc.2008.05.013 BindingDB Entry DOI: 10.7270/Q2K07569
					More data for this Ligand-Target Pair
Purinergic receptor P2Y2 (Homo sapiens (Human))	BDBM50270549 (CHEMBL503256 | P1-((2-benzyl-1,3-dioxolo-4-yl)urid...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@@H]2OC(Cc3ccccc3)O[C@H]12)n1ccc(=O)[nH]c1=O)n1cc(I)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C26H30IN4O20P3/c27-13-9-31(26(37)29-22(13)35)23-19(34)18(33)14(46-23)10-44-52(38,39)50-54(42,43)51-53(40,41)45-11-15-20-21(24(47-15)30-7-6-16(32)28-25(30)36)49-17(48-20)8-12-4-2-1-3-5-12/h1-7,9,14-15,17-21,23-24,33-34H,8,10-11H2,(H,38,39)(H,40,41)(H,42,43)(H,28,32,36)(H,29,35,37)/t14-,15-,17?,18-,19-,20-,21-,23-,24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.97E+3	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...				Bioorg Med Chem 16: 6319-32 (2008) Article DOI: 10.1016/j.bmc.2008.05.013 BindingDB Entry DOI: 10.7270/Q2K07569
					More data for this Ligand-Target Pair