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BDBM50270753 CHEMBL485886::Indan-2-ylcarbamic Acid Biphenyl-3-yl Ester

SMILES: O=C(NC1Cc2ccccc2C1)Oc1cccc(c1)-c1ccccc1

InChI Key: InChIKey=UEEYQEMKIXZIGW-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270753   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 (aa 30-579)


(Rattus norvegicus (rat))
BDBM50270753
PNG
(CHEMBL485886 | Indan-2-ylcarbamic Acid Biphenyl-3-...)
Show SMILES O=C(NC1Cc2ccccc2C1)Oc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C22H19NO2/c24-22(23-20-13-17-9-4-5-10-18(17)14-20)25-21-12-6-11-19(15-21)16-7-2-1-3-8-16/h1-12,15,20H,13-14H2,(H,23,24)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 214n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]-anandamide from rat brain FAAH after 30 mins by scintillation counting


Eur J Med Chem 46: 4466-73 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.021
BindingDB Entry DOI: 10.7270/Q2FB546B
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579)


(Rattus norvegicus (rat))
BDBM50270753
PNG
(CHEMBL485886 | Indan-2-ylcarbamic Acid Biphenyl-3-...)
Show SMILES O=C(NC1Cc2ccccc2C1)Oc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C22H19NO2/c24-22(23-20-13-17-9-4-5-10-18(17)14-20)25-21-12-6-11-19(15-21)16-7-2-1-3-8-16/h1-12,15,20H,13-14H2,(H,23,24)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 215n/an/an/an/an/an/a



Università degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membrane assessed as [3H]anandamide hydrolysis


J Med Chem 51: 3487-98 (2008)


Article DOI: 10.1021/jm701631z
BindingDB Entry DOI: 10.7270/Q2TM79W9
More data for this
Ligand-Target Pair