BDBM50271030 3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcarbamate::CHEMBL483697::Naphthalen-2-ylmethylcarbamic Acid 3'-Carbamoylbiphenyl-3-yl Ester

SMILES: NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1

InChI Key: InChIKey=HSPABSYTWRUCGU-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50271030 (3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcar...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C25H20N2O3/c26-24(28)22-9-3-7-20(14-22)21-8-4-10-23(15-21)30-25(29)27-16-17-11-12-18-5-1-2-6-19(18)13-17/h1-15H,16H2,(H2,26,28)(H,27,29)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of FAAH in rat brain membrane assessed as [3H]anandamide hydrolysis				J Med Chem 51: 3487-98 (2008) Article DOI: 10.1021/jm701631z BindingDB Entry DOI: 10.7270/Q2TM79W9
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50271030 (3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcar...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C25H20N2O3/c26-24(28)22-9-3-7-20(14-22)21-8-4-10-23(15-21)30-25(29)27-16-17-11-12-18-5-1-2-6-19(18)13-17/h1-15H,16H2,(H2,26,28)(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50271030 (3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcar...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C25H20N2O3/c26-24(28)22-9-3-7-20(14-22)21-8-4-10-23(15-21)30-25(29)27-16-17-11-12-18-5-1-2-6-19(18)13-17/h1-15H,16H2,(H2,26,28)(H,27,29)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.631	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]-anandamide from rat brain FAAH after 30 mins by scintillation counting				Eur J Med Chem 46: 4466-73 (2011) Article DOI: 10.1016/j.ejmech.2011.07.021 BindingDB Entry DOI: 10.7270/Q2FB546B
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50271030 (3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcar...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C25H20N2O3/c26-24(28)22-9-3-7-20(14-22)21-8-4-10-23(15-21)30-25(29)27-16-17-11-12-18-5-1-2-6-19(18)13-17/h1-15H,16H2,(H2,26,28)(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of monoglyceride lipase in rat brain membrane				J Med Chem 51: 3487-98 (2008) Article DOI: 10.1021/jm701631z BindingDB Entry DOI: 10.7270/Q2TM79W9
					More data for this Ligand-Target Pair