BDBM50271314 2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohex-1-enecarboxylic acid::CHEMBL482698

SMILES: OC(=O)C1=C(CCCC1)NC(=O)CCc1ccc2cc(O)ccc2c1

InChI Key: InChIKey=ALVRTKGVHQDHNJ-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50271314 (2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohe...) Show SMILES OC(=O)C1=C(CCCC1)NC(=O)CCc1ccc2cc(O)ccc2c1 |t:3| Show InChI InChI=1S/C20H21NO4/c22-16-9-8-14-11-13(5-7-15(14)12-16)6-10-19(23)21-18-4-2-1-3-17(18)20(24)25/h5,7-9,11-12,22H,1-4,6,10H2,(H,21,23)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Latvian Institute of Organic Synthesis Curated by ChEMBL					Assay Description Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins				Bioorg Med Chem 22: 3654-69 (2014) Article DOI: 10.1016/j.bmc.2014.05.011 BindingDB Entry DOI: 10.7270/Q21J9CCB
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50271314 (2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohe...) Show SMILES OC(=O)C1=C(CCCC1)NC(=O)CCc1ccc2cc(O)ccc2c1 |t:3| Show InChI InChI=1S/C20H21NO4/c22-16-9-8-14-11-13(5-7-15(14)12-16)6-10-19(23)21-18-4-2-1-3-17(18)20(24)25/h5,7-9,11-12,22H,1-4,6,10H2,(H,21,23)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 20: 3426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.04.001 BindingDB Entry DOI: 10.7270/Q2W0963X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50271314 (2-(3-(6-hydroxynaphthalen-2-yl)propanamido)cyclohe...) Show SMILES OC(=O)C1=C(CCCC1)NC(=O)CCc1ccc2cc(O)ccc2c1 |t:3| Show InChI InChI=1S/C20H21NO4/c22-16-9-8-14-11-13(5-7-15(14)12-16)6-10-19(23)21-18-4-2-1-3-17(18)20(24)25/h5,7-9,11-12,22H,1-4,6,10H2,(H,21,23)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human niacin receptor expressed in CHO-KI cells				Bioorg Med Chem Lett 20: 3426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.04.001 BindingDB Entry DOI: 10.7270/Q2W0963X
					More data for this Ligand-Target Pair