BDBM50271610 CHEMBL418695

SMILES: O=C1NC(=O)C(Cc2ccc(OCCn3ccc4ccccc34)cc2)S1

InChI Key: InChIKey=PCAZCAZVHLGDBA-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271610 (CHEMBL418695) Show SMILES O=C1NC(=O)C(Cc2ccc(OCCn3ccc4ccccc34)cc2)S1 Show InChI InChI=1S/C20H18N2O3S/c23-19-18(26-20(24)21-19)13-14-5-7-16(8-6-14)25-12-11-22-10-9-15-3-1-2-4-17(15)22/h1-10,18H,11-13H2,(H,21,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50271610 (CHEMBL418695) Show SMILES O=C1NC(=O)C(Cc2ccc(OCCn3ccc4ccccc34)cc2)S1 Show InChI InChI=1S/C20H18N2O3S/c23-19-18(26-20(24)21-19)13-14-5-7-16(8-6-14)25-12-11-22-10-9-15-3-1-2-4-17(15)22/h1-10,18H,11-13H2,(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.94E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
					More data for this Ligand-Target Pair