BDBM50271659 CHEMBL4127388

SMILES: CCN(CC)CCCNC(=O)c1ccc(OC)c(c1)[N+]([O-])=O

InChI Key: InChIKey=CGELBKRUWLJWAL-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50271659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PRMT5/MEP50 Enzyme (Homo sapiens (Human))	BDBM50271659 (CHEMBL4127388) Show SMILES CCN(CC)CCCNC(=O)c1ccc(OC)c(c1)[N+]([O-])=O Show InChI InChI=1S/C15H23N3O4/c1-4-17(5-2)10-6-9-16-15(19)12-7-8-14(22-3)13(11-12)18(20)21/h7-8,11H,4-6,9-10H2,1-3H3,(H,16,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Jinan Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in ...				Bioorg Med Chem Lett 28: 1476-1483 (2018) Article DOI: 10.1016/j.bmcl.2018.03.087 BindingDB Entry DOI: 10.7270/Q2CN76D3
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