BDBM50272114 4-(5-chloro-3-(3-chlorophenyl)-1H-indol-2-yl)benzenesulfonamide::CHEMBL524542

SMILES: NS(=O)(=O)c1ccc(cc1)-c1[nH]c2ccc(Cl)cc2c1-c1cccc(Cl)c1

InChI Key: InChIKey=KLGAEMROZJNCFW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase (cyclooxygenase) (Mus musculus (Mouse))	BDBM50272114 (4-(5-chloro-3-(3-chlorophenyl)-1H-indol-2-yl)benze...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1[nH]c2ccc(Cl)cc2c1-c1cccc(Cl)c1 Show InChI InChI=1S/C20H14Cl2N2O2S/c21-14-3-1-2-13(10-14)19-17-11-15(22)6-9-18(17)24-20(19)12-4-7-16(8-5-12)27(23,25)26/h1-11,24H,(H2,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage				Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50272114 (4-(5-chloro-3-(3-chlorophenyl)-1H-indol-2-yl)benze...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1[nH]c2ccc(Cl)cc2c1-c1cccc(Cl)c1 Show InChI InChI=1S/C20H14Cl2N2O2S/c21-14-3-1-2-13(10-14)19-17-11-15(22)6-9-18(17)24-20(19)12-4-7-16(8-5-12)27(23,25)26/h1-11,24H,(H2,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.13	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of COX2 (unknown origin)				Eur J Med Chem 43: 1297-303 (2008) Article DOI: 10.1016/j.ejmech.2007.06.022 BindingDB Entry DOI: 10.7270/Q2CC10F1
					More data for this Ligand-Target Pair