BDBM50272793 (+/-)-1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(2-methylcyclohexylidene)hydrazine::CHEMBL1242936::CHEMBL496279

SMILES: CC1CCCCC1=NNc1nc(cs1)-c1ccc(Cl)cc1

InChI Key: InChIKey=JBCSKFKLXZHIIW-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50272793 ((+/-)-1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(2-meth...) Show SMILES CC1CCCCC1=NNc1nc(cs1)-c1ccc(Cl)cc1 |w:7.8| Show InChI InChI=1S/C16H18ClN3S/c1-11-4-2-3-5-14(11)19-20-16-18-15(10-21-16)12-6-8-13(17)9-7-12/h6-11H,2-5H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 51: 4874-80 (2008) Article DOI: 10.1021/jm800132g BindingDB Entry DOI: 10.7270/Q27P8Z5J
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50272793 ((+/-)-1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(2-meth...) Show SMILES CC1CCCCC1=NNc1nc(cs1)-c1ccc(Cl)cc1 |w:7.8| Show InChI InChI=1S/C16H18ClN3S/c1-11-4-2-3-5-14(11)19-20-16-18-15(10-21-16)12-6-8-13(17)9-7-12/h6-11H,2-5H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB				J Med Chem 51: 4874-80 (2008) Article DOI: 10.1021/jm800132g BindingDB Entry DOI: 10.7270/Q27P8Z5J
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50272793 ((+/-)-1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(2-meth...) Show SMILES CC1CCCCC1=NNc1nc(cs1)-c1ccc(Cl)cc1 |w:7.8| Show InChI InChI=1S/C16H18ClN3S/c1-11-4-2-3-5-14(11)19-20-16-18-15(10-21-16)12-6-8-13(17)9-7-12/h6-11H,2-5H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica e Tecnologie del Farmaco Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...				Bioorg Med Chem 18: 5063-70 (2010) Article DOI: 10.1016/j.bmc.2010.05.070 BindingDB Entry DOI: 10.7270/Q22F7PD1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50272793 ((+/-)-1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(2-meth...) Show SMILES CC1CCCCC1=NNc1nc(cs1)-c1ccc(Cl)cc1 |w:7.8| Show InChI InChI=1S/C16H18ClN3S/c1-11-4-2-3-5-14(11)19-20-16-18-15(10-21-16)12-6-8-13(17)9-7-12/h6-11H,2-5H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...				J Med Chem 53: 6516-20 (2010) Article DOI: 10.1021/jm100120s BindingDB Entry DOI: 10.7270/Q26H4HNW
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50272793 ((+/-)-1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(2-meth...) Show SMILES CC1CCCCC1=NNc1nc(cs1)-c1ccc(Cl)cc1 |w:7.8| Show InChI InChI=1S/C16H18ClN3S/c1-11-4-2-3-5-14(11)19-20-16-18-15(10-21-16)12-6-8-13(17)9-7-12/h6-11H,2-5H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Chimica e Tecnologie del Farmaco Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...				Bioorg Med Chem 18: 5063-70 (2010) Article DOI: 10.1016/j.bmc.2010.05.070 BindingDB Entry DOI: 10.7270/Q22F7PD1
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50272793 ((+/-)-1-(4-(4-chlorophenyl)thiazol-2-yl)-2-(2-meth...) Show SMILES CC1CCCCC1=NNc1nc(cs1)-c1ccc(Cl)cc1 |w:7.8| Show InChI InChI=1S/C16H18ClN3S/c1-11-4-2-3-5-14(11)19-20-16-18-15(10-21-16)12-6-8-13(17)9-7-12/h6-11H,2-5H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...				J Med Chem 53: 6516-20 (2010) Article DOI: 10.1021/jm100120s BindingDB Entry DOI: 10.7270/Q26H4HNW
					More data for this Ligand-Target Pair