BDBM50272961 CHEMBL4129923

SMILES: NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2F)cc1

InChI Key: InChIKey=UQWPEIHBSUTBJS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50272961 (CHEMBL4129923) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2F)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-23-7-2-1-6-22(23)17-12-14-28(15-13-17)25(30)19-4-3-5-21(16-19)31-20-10-8-18(9-11-20)24(27)29/h1-11,16-17H,12-15H2,(H2,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50272961 (CHEMBL4129923) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2F)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-23-7-2-1-6-22(23)17-12-14-28(15-13-17)25(30)19-4-3-5-21(16-19)31-20-10-8-18(9-11-20)24(27)29/h1-11,16-17H,12-15H2,(H2,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair