BDBM50272962 CHEMBL4129939

SMILES: CCOC(=O)C1CCN(CC1)C(=O)c1cccc(Oc2ccc(cc2)C(N)=O)c1

InChI Key: InChIKey=URKPVAZPUPFVGX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50272962 (CHEMBL4129939) Show SMILES CCOC(=O)C1CCN(CC1)C(=O)c1cccc(Oc2ccc(cc2)C(N)=O)c1 Show InChI InChI=1S/C22H24N2O5/c1-2-28-22(27)16-10-12-24(13-11-16)21(26)17-4-3-5-19(14-17)29-18-8-6-15(7-9-18)20(23)25/h3-9,14,16H,2,10-13H2,1H3,(H2,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50272962 (CHEMBL4129939) Show SMILES CCOC(=O)C1CCN(CC1)C(=O)c1cccc(Oc2ccc(cc2)C(N)=O)c1 Show InChI InChI=1S/C22H24N2O5/c1-2-28-22(27)16-10-12-24(13-11-16)21(26)17-4-3-5-19(14-17)29-18-8-6-15(7-9-18)20(23)25/h3-9,14,16H,2,10-13H2,1H3,(H2,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair