BDBM50272965 CHEMBL4127327

SMILES: NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1

InChI Key: InChIKey=UBISEXDTBVRYHF-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50272965 (CHEMBL4127327) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H24N2O3/c26-24(28)20-9-11-22(12-10-20)30-23-8-4-7-21(17-23)25(29)27-15-13-19(14-16-27)18-5-2-1-3-6-18/h1-12,17,19H,13-16H2,(H2,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50272965 (CHEMBL4127327) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H24N2O3/c26-24(28)20-9-11-22(12-10-20)30-23-8-4-7-21(17-23)25(29)27-15-13-19(14-16-27)18-5-2-1-3-6-18/h1-12,17,19H,13-16H2,(H2,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50272965 (CHEMBL4127327) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H24N2O3/c26-24(28)20-9-11-22(12-10-20)30-23-8-4-7-21(17-23)25(29)27-15-13-19(14-16-27)18-5-2-1-3-6-18/h1-12,17,19H,13-16H2,(H2,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50272965 (CHEMBL4127327) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H24N2O3/c26-24(28)20-9-11-22(12-10-20)30-23-8-4-7-21(17-23)25(29)27-15-13-19(14-16-27)18-5-2-1-3-6-18/h1-12,17,19H,13-16H2,(H2,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair