BDBM50272969 CHEMBL4129542

SMILES: NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(C2)c2ccccc2)cc1

InChI Key: InChIKey=WDWIGSXTKMTQPI-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50272969 (CHEMBL4129542) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(C2)c2ccccc2)cc1 Show InChI InChI=1S/C24H22N2O3/c25-23(27)18-9-11-21(12-10-18)29-22-8-4-7-19(15-22)24(28)26-14-13-20(16-26)17-5-2-1-3-6-17/h1-12,15,20H,13-14,16H2,(H2,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50272969 (CHEMBL4129542) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(C2)c2ccccc2)cc1 Show InChI InChI=1S/C24H22N2O3/c25-23(27)18-9-11-21(12-10-18)29-22-8-4-7-19(15-22)24(28)26-14-13-20(16-26)17-5-2-1-3-6-17/h1-12,15,20H,13-14,16H2,(H2,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50272969 (CHEMBL4129542) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(C2)c2ccccc2)cc1 Show InChI InChI=1S/C24H22N2O3/c25-23(27)18-9-11-21(12-10-18)29-22-8-4-7-19(15-22)24(28)26-14-13-20(16-26)17-5-2-1-3-6-17/h1-12,15,20H,13-14,16H2,(H2,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50272969 (CHEMBL4129542) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(C2)c2ccccc2)cc1 Show InChI InChI=1S/C24H22N2O3/c25-23(27)18-9-11-21(12-10-18)29-22-8-4-7-19(15-22)24(28)26-14-13-20(16-26)17-5-2-1-3-6-17/h1-12,15,20H,13-14,16H2,(H2,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	776	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...				Bioorg Med Chem Lett 28: 2050-2054 (2018) Article DOI: 10.1016/j.bmcl.2018.04.056 BindingDB Entry DOI: 10.7270/Q2RR21R2
					More data for this Ligand-Target Pair