BDBM50273052 2-((tert-butylamino)methyl)-N-(4-(trifluoromethyl)phenyl)-7-(3-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine::CHEMBL456546

SMILES: CC(C)(C)NCc1nc(Nc2ccc(cc2)C(F)(F)F)c2ccc(cc2n1)-c1ncccc1C(F)(F)F

InChI Key: InChIKey=BOOADBNNIFRSQO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273052 (2-((tert-butylamino)methyl)-N-(4-(trifluoromethyl)...) Show SMILES CC(C)(C)NCc1nc(Nc2ccc(cc2)C(F)(F)F)c2ccc(cc2n1)-c1ncccc1C(F)(F)F Show InChI InChI=1S/C26H23F6N5/c1-24(2,3)34-14-21-36-20-13-15(22-19(26(30,31)32)5-4-12-33-22)6-11-18(20)23(37-21)35-17-9-7-16(8-10-17)25(27,28)29/h4-13,34H,14H2,1-3H3,(H,35,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced activation				Bioorg Med Chem Lett 18: 4573-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.036 BindingDB Entry DOI: 10.7270/Q28P6099
					More data for this Ligand-Target Pair