BDBM50273419 (+)-(4aR,10aR)-trans-4-(2-(4-Phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octa-hydrobenzo[f]quinolin-7-ol::CHEMBL513931

SMILES: Oc1cccc2[C@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@@H]3CCc12

InChI Key: InChIKey=QQRPTUXXSDJYLW-ISKFKSNPSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50273419 ((+)-(4aR,10aR)-trans-4-(2-(4-Phenylpiperazin-1-yl)...) Show SMILES Oc1cccc2[C@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@@H]3CCc12 |r| Show InChI InChI=1S/C25H33N3O/c29-25-10-4-8-21-22-9-5-13-28(24(22)12-11-23(21)25)19-16-26-14-17-27(18-15-26)20-6-2-1-3-7-20/h1-4,6-8,10,22,24,29H,5,9,11-19H2/t22-,24-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from rat dopamine D3 receptor expressed in HEK293 cells				J Med Chem 51: 7806-19 (2008) Article DOI: 10.1021/jm8008629 BindingDB Entry DOI: 10.7270/Q22B8XWJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50273419 ((+)-(4aR,10aR)-trans-4-(2-(4-Phenylpiperazin-1-yl)...) Show SMILES Oc1cccc2[C@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@@H]3CCc12 |r| Show InChI InChI=1S/C25H33N3O/c29-25-10-4-8-21-22-9-5-13-28(24(22)12-11-23(21)25)19-16-26-14-17-27(18-15-26)20-6-2-1-3-7-20/h1-4,6-8,10,22,24,29H,5,9,11-19H2/t22-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	835	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from rat dopamine D2L receptor expressed in HEK293 cells				J Med Chem 51: 7806-19 (2008) Article DOI: 10.1021/jm8008629 BindingDB Entry DOI: 10.7270/Q22B8XWJ
					More data for this Ligand-Target Pair