BDBM50273551 CHEMBL4129143

SMILES: ONC(=O)c1cccc2CN(Cc12)c1ccc(cn1)C(F)(F)F

InChI Key: InChIKey=IPSMKDVVNSAVIF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50273551 (CHEMBL4129143) Show SMILES ONC(=O)c1cccc2CN(Cc12)c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C15H12F3N3O2/c16-15(17,18)10-4-5-13(19-6-10)21-7-9-2-1-3-11(12(9)8-21)14(22)20-23/h1-6,23H,7-8H2,(H,20,22)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics Curated by ChEMBL					Assay Description Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...				Bioorg Med Chem Lett 28: 2143-2147 (2018) Article DOI: 10.1016/j.bmcl.2018.05.021 BindingDB Entry DOI: 10.7270/Q2PR7ZGX
					More data for this Ligand-Target Pair