BDBM50273554 CHEMBL4129134

SMILES: CC1(C)N(Cc2c1cccc2C(=O)NO)c1ccc(cn1)C(F)(F)F

InChI Key: InChIKey=LKTXDGRWJDTGPL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50273554 (CHEMBL4129134) Show SMILES CC1(C)N(Cc2c1cccc2C(=O)NO)c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C17H16F3N3O2/c1-16(2)13-5-3-4-11(15(24)22-25)12(13)9-23(16)14-7-6-10(8-21-14)17(18,19)20/h3-8,25H,9H2,1-2H3,(H,22,24)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics Curated by ChEMBL					Assay Description Inhibition of NanoLuc-tagged HDAC11 (unknown origin) by BRET assay				Bioorg Med Chem Lett 28: 2143-2147 (2018) Article DOI: 10.1016/j.bmcl.2018.05.021 BindingDB Entry DOI: 10.7270/Q2PR7ZGX
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50273554 (CHEMBL4129134) Show SMILES CC1(C)N(Cc2c1cccc2C(=O)NO)c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C17H16F3N3O2/c1-16(2)13-5-3-4-11(15(24)22-25)12(13)9-23(16)14-7-6-10(8-21-14)17(18,19)20/h3-8,25H,9H2,1-2H3,(H,22,24)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics Curated by ChEMBL					Assay Description Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...				Bioorg Med Chem Lett 28: 2143-2147 (2018) Article DOI: 10.1016/j.bmcl.2018.05.021 BindingDB Entry DOI: 10.7270/Q2PR7ZGX
					More data for this Ligand-Target Pair