BDBM50273646 CHEMBL4126698

SMILES: Cc1noc(C)c1-c1cc(O)cc(c1)C(O)c1ccc(Cl)cn1

InChI Key: InChIKey=HDZUDLHMKDHTLY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50273646 (CHEMBL4126698) Show SMILES Cc1noc(C)c1-c1cc(O)cc(c1)C(O)c1ccc(Cl)cn1 Show InChI InChI=1S/C17H15ClN2O3/c1-9-16(10(2)23-20-9)11-5-12(7-14(21)6-11)17(22)15-4-3-13(18)8-19-15/h3-8,17,21-22H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	495	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged human BRD4 bromodomain 1 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells preincubated for 30 mins follo...				Bioorg Med Chem 26: 2937-2957 (2018) Article DOI: 10.1016/j.bmc.2018.05.003 BindingDB Entry DOI: 10.7270/Q2Z89FXZ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50273646 (CHEMBL4126698) Show SMILES Cc1noc(C)c1-c1cc(O)cc(c1)C(O)c1ccc(Cl)cn1 Show InChI InChI=1S/C17H15ClN2O3/c1-9-16(10(2)23-20-9)11-5-12(7-14(21)6-11)17(22)15-4-3-13(18)8-19-15/h3-8,17,21-22H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged human BRD4 bromodomain 1 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells preincubated for 30 mins follo...				Bioorg Med Chem 26: 2937-2957 (2018) Article DOI: 10.1016/j.bmc.2018.05.003 BindingDB Entry DOI: 10.7270/Q2Z89FXZ
					More data for this Ligand-Target Pair