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BDBM50273758 (4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S,46S,49S,52S,58S)-4-((6S,12S,15S,18S,21S,24S,27S,30S,31S)-21-((1H-indol-3-yl)methyl)-1-amino-12-(4-aminobutyl)-27-benzyl-6-carbamoyl-1-imino-18-isobutyl-15-isopropyl-24,31-dimethyl-8,11,14,17,20,23,26,29-octaoxo-2,7,10,13,16,19,22,25,28-nonaazatritriacontan-30-ylcarbamoyl)-37-(4-acetamidobutyl)-58-((S)-2-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)propanamido)-16,25-bis(3-amino-3-oxopropyl)-7-(4-aminobutyl)-49-benzyl-22-(2-carboxyethyl)-40-(carb::CHEMBL526516

SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O

InChI Key: InChIKey=OWDILLAJRMQULG-WXFSEBKWSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273758   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))		BDBM50273758
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O |r,wU:154.156,140.147,132.134,162.166,117.118,165.169,103.108,85.88,67.76,49.54,36.41,26.26,8.13,2.2,171.173,187.190,209.214,wD:149.151,121.130,111.114,91.100,79.82,58.63,31.31,17.22,4.4,182.186,201.206,216.221,229.234,(75.54,-8.31,;75.54,-6.76,;76.88,-6,;78.21,-6.77,;76.88,-4.46,;75.54,-3.7,;74.21,-4.47,;74.21,-6,;72.88,-3.69,;72.88,-2.15,;74.21,-1.38,;74.21,.16,;72.87,.93,;75.54,.92,;71.54,-4.47,;70.21,-3.7,;70.21,-2.16,;68.87,-4.47,;68.87,-6.01,;70.21,-6.78,;70.21,-8.31,;71.54,-9.09,;71.54,-10.62,;67.54,-3.7,;66.21,-4.47,;66.21,-6.01,;64.88,-3.71,;64.88,-2.16,;63.54,-4.48,;62.21,-3.71,;62.21,-2.17,;60.87,-4.48,;60.87,-6.02,;59.54,-3.71,;58.2,-4.48,;58.2,-6.02,;56.87,-3.72,;56.87,-2.18,;58.2,-1.4,;58.2,.14,;56.86,.91,;59.54,.91,;55.54,-4.49,;54.21,-3.72,;54.21,-2.17,;52.86,-4.49,;51.54,-3.73,;50.2,-4.5,;50.2,-6.03,;48.87,-3.72,;48.87,-2.18,;50.2,-1.41,;50.2,.13,;48.86,.9,;51.54,.89,;47.54,-4.5,;46.2,-3.73,;46.2,-2.19,;44.87,-4.5,;44.87,-6.04,;46.2,-6.81,;46.2,-8.34,;44.87,-9.12,;47.54,-9.12,;43.53,-3.73,;42.2,-4.5,;42.2,-6.04,;40.87,-3.74,;40.87,-2.19,;42.2,-1.43,;43.53,-2.19,;44.86,-1.42,;44.86,.12,;46.2,.89,;43.52,.89,;42.2,.12,;39.53,-4.51,;38.2,-3.74,;38.2,-2.2,;36.87,-4.51,;36.87,-6.05,;38.2,-6.82,;35.53,-3.74,;34.19,-4.52,;34.19,-6.05,;32.87,-3.75,;32.87,-2.21,;34.19,-1.43,;31.53,-4.52,;30.2,-3.75,;30.2,-2.2,;28.86,-4.52,;28.86,-6.06,;30.2,-6.83,;30.2,-8.37,;31.53,-9.14,;31.53,-10.67,;30.2,-11.44,;30.2,-12.98,;28.87,-10.67,;27.53,-3.76,;26.2,-4.53,;26.2,-6.06,;24.86,-3.75,;24.86,-2.21,;26.2,-1.45,;27.52,-2.21,;26.2,.1,;23.52,-4.53,;22.2,-3.76,;22.2,-2.22,;20.86,-4.53,;20.86,-6.07,;22.2,-6.84,;19.52,-3.76,;18.19,-4.53,;18.19,-6.07,;16.86,-3.77,;15.52,-4.54,;14.19,-3.77,;14.19,-2.23,;12.85,-4.54,;12.85,-6.08,;14.19,-6.85,;15.52,-6.08,;16.86,-6.84,;16.86,-8.38,;15.53,-9.15,;14.2,-8.39,;11.53,-3.77,;10.19,-4.55,;10.19,-6.08,;8.85,-3.78,;7.52,-4.55,;6.19,-3.78,;6.19,-2.23,;4.85,-4.55,;3.53,-3.79,;2.18,-4.56,;2.18,-6.09,;.85,-3.78,;.85,-2.24,;2.18,-1.48,;2.18,.07,;.85,.84,;3.52,.83,;-.48,-4.56,;-1.81,-3.79,;-1.81,-2.25,;-3.15,-4.56,;-3.15,-6.1,;-4.48,-3.79,;-5.82,-4.57,;-5.82,-6.1,;-7.15,-3.79,;-8.49,-4.56,;-7.15,-2.25,;-5.82,-1.49,;-4.42,-2.11,;-3.38,-.97,;-4.15,.37,;-5.66,.05,;8.85,-2.24,;7.52,-1.46,;10.19,-1.46,;16.86,-2.22,;15.52,-1.45,;18.19,-1.46,;78.21,-3.69,;78.21,-2.14,;79.54,-4.46,;80.88,-3.69,;80.88,-2.15,;82.21,-1.37,;83.54,-2.14,;84.88,-1.37,;84.88,.17,;83.54,.93,;82.21,.16,;82.21,-4.45,;82.21,-5.99,;83.55,-3.68,;84.88,-4.45,;84.88,-5.99,;86.21,-3.68,;86.21,-2.14,;87.55,-4.45,;88.89,-3.68,;88.89,-2.14,;90.21,-1.37,;91.62,-1.99,;92.65,-.84,;91.88,.49,;92.35,1.96,;91.32,3.1,;89.82,2.78,;89.34,1.31,;90.37,.17,;90.21,-4.44,;90.21,-5.98,;91.55,-3.67,;92.88,-4.45,;92.88,-5.98,;94.22,-6.75,;94.22,-8.28,;95.56,-5.98,;94.22,-3.67,;94.22,-2.13,;95.55,-4.44,;96.88,-3.67,;96.88,-2.12,;98.22,-1.36,;95.55,-1.35,;98.22,-4.44,;98.22,-5.97,;99.56,-3.67,;100.88,-4.43,;100.88,-5.97,;102.22,-6.74,;102.22,-8.28,;103.56,-9.05,;103.56,-10.58,;102.22,-3.66,;102.22,-2.12,;103.56,-4.43,;104.88,-3.66,;106.22,-4.43,;106.22,-5.97,;107.56,-3.66,;108.88,-4.42,;108.88,-5.96,;110.23,-6.73,;110.23,-8.27,;111.56,-9.04,;111.56,-10.58,;110.23,-11.34,;112.9,-11.35,;110.23,-3.65,;111.55,-4.42,;110.23,-2.11,)|
Show InChI InChI=1S/C151H228N42O47/c1-14-76(6)121(148(238)185-103(59-84-30-17-15-18-31-84)138(228)171-80(10)128(218)181-106(62-87-65-163-92-35-22-21-34-90(87)92)140(230)182-102(58-74(2)3)142(232)191-120(75(4)5)147(237)180-94(36-23-26-54-152)130(220)164-67-113(203)172-93(124(157)214)39-29-57-162-151(158)159)192-137(227)101(48-53-118(210)211)178-134(224)95(37-24-27-55-153)174-126(216)78(8)168-125(215)77(7)170-133(223)99(44-49-111(155)201)173-114(204)68-165-132(222)98(47-52-117(208)209)177-136(226)100(45-50-112(156)202)179-139(229)104(61-86-40-42-89(200)43-41-86)183-144(234)108(70-194)188-146(236)109(71-195)187-135(225)96(38-25-28-56-161-83(13)199)176-141(231)107(64-119(212)213)184-145(235)110(72-196)189-150(240)123(82(12)198)193-143(233)105(60-85-32-19-16-20-33-85)186-149(239)122(81(11)197)190-115(205)69-166-131(221)97(46-51-116(206)207)175-127(217)79(9)169-129(219)91(154)63-88-66-160-73-167-88/h15-22,30-35,40-43,65-66,73-82,91,93-110,120-123,163,194-198,200H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,201)(H2,156,202)(H2,157,214)(H,160,167)(H,161,199)(H,164,220)(H,165,222)(H,166,221)(H,168,215)(H,169,219)(H,170,223)(H,171,228)(H,172,203)(H,173,204)(H,174,216)(H,175,217)(H,176,231)(H,177,226)(H,178,224)(H,179,229)(H,180,237)(H,181,218)(H,182,230)(H,183,234)(H,184,235)(H,185,238)(H,186,239)(H,187,225)(H,188,236)(H,189,240)(H,190,205)(H,191,232)(H,192,227)(H,193,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,158,159,162)/t76-,77-,78-,79-,80-,81+,82+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells

Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))		BDBM50273758
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O |r,wU:154.156,140.147,132.134,162.166,117.118,165.169,103.108,85.88,67.76,49.54,36.41,26.26,8.13,2.2,171.173,187.190,209.214,wD:149.151,121.130,111.114,91.100,79.82,58.63,31.31,17.22,4.4,182.186,201.206,216.221,229.234,(75.54,-8.31,;75.54,-6.76,;76.88,-6,;78.21,-6.77,;76.88,-4.46,;75.54,-3.7,;74.21,-4.47,;74.21,-6,;72.88,-3.69,;72.88,-2.15,;74.21,-1.38,;74.21,.16,;72.87,.93,;75.54,.92,;71.54,-4.47,;70.21,-3.7,;70.21,-2.16,;68.87,-4.47,;68.87,-6.01,;70.21,-6.78,;70.21,-8.31,;71.54,-9.09,;71.54,-10.62,;67.54,-3.7,;66.21,-4.47,;66.21,-6.01,;64.88,-3.71,;64.88,-2.16,;63.54,-4.48,;62.21,-3.71,;62.21,-2.17,;60.87,-4.48,;60.87,-6.02,;59.54,-3.71,;58.2,-4.48,;58.2,-6.02,;56.87,-3.72,;56.87,-2.18,;58.2,-1.4,;58.2,.14,;56.86,.91,;59.54,.91,;55.54,-4.49,;54.21,-3.72,;54.21,-2.17,;52.86,-4.49,;51.54,-3.73,;50.2,-4.5,;50.2,-6.03,;48.87,-3.72,;48.87,-2.18,;50.2,-1.41,;50.2,.13,;48.86,.9,;51.54,.89,;47.54,-4.5,;46.2,-3.73,;46.2,-2.19,;44.87,-4.5,;44.87,-6.04,;46.2,-6.81,;46.2,-8.34,;44.87,-9.12,;47.54,-9.12,;43.53,-3.73,;42.2,-4.5,;42.2,-6.04,;40.87,-3.74,;40.87,-2.19,;42.2,-1.43,;43.53,-2.19,;44.86,-1.42,;44.86,.12,;46.2,.89,;43.52,.89,;42.2,.12,;39.53,-4.51,;38.2,-3.74,;38.2,-2.2,;36.87,-4.51,;36.87,-6.05,;38.2,-6.82,;35.53,-3.74,;34.19,-4.52,;34.19,-6.05,;32.87,-3.75,;32.87,-2.21,;34.19,-1.43,;31.53,-4.52,;30.2,-3.75,;30.2,-2.2,;28.86,-4.52,;28.86,-6.06,;30.2,-6.83,;30.2,-8.37,;31.53,-9.14,;31.53,-10.67,;30.2,-11.44,;30.2,-12.98,;28.87,-10.67,;27.53,-3.76,;26.2,-4.53,;26.2,-6.06,;24.86,-3.75,;24.86,-2.21,;26.2,-1.45,;27.52,-2.21,;26.2,.1,;23.52,-4.53,;22.2,-3.76,;22.2,-2.22,;20.86,-4.53,;20.86,-6.07,;22.2,-6.84,;19.52,-3.76,;18.19,-4.53,;18.19,-6.07,;16.86,-3.77,;15.52,-4.54,;14.19,-3.77,;14.19,-2.23,;12.85,-4.54,;12.85,-6.08,;14.19,-6.85,;15.52,-6.08,;16.86,-6.84,;16.86,-8.38,;15.53,-9.15,;14.2,-8.39,;11.53,-3.77,;10.19,-4.55,;10.19,-6.08,;8.85,-3.78,;7.52,-4.55,;6.19,-3.78,;6.19,-2.23,;4.85,-4.55,;3.53,-3.79,;2.18,-4.56,;2.18,-6.09,;.85,-3.78,;.85,-2.24,;2.18,-1.48,;2.18,.07,;.85,.84,;3.52,.83,;-.48,-4.56,;-1.81,-3.79,;-1.81,-2.25,;-3.15,-4.56,;-3.15,-6.1,;-4.48,-3.79,;-5.82,-4.57,;-5.82,-6.1,;-7.15,-3.79,;-8.49,-4.56,;-7.15,-2.25,;-5.82,-1.49,;-4.42,-2.11,;-3.38,-.97,;-4.15,.37,;-5.66,.05,;8.85,-2.24,;7.52,-1.46,;10.19,-1.46,;16.86,-2.22,;15.52,-1.45,;18.19,-1.46,;78.21,-3.69,;78.21,-2.14,;79.54,-4.46,;80.88,-3.69,;80.88,-2.15,;82.21,-1.37,;83.54,-2.14,;84.88,-1.37,;84.88,.17,;83.54,.93,;82.21,.16,;82.21,-4.45,;82.21,-5.99,;83.55,-3.68,;84.88,-4.45,;84.88,-5.99,;86.21,-3.68,;86.21,-2.14,;87.55,-4.45,;88.89,-3.68,;88.89,-2.14,;90.21,-1.37,;91.62,-1.99,;92.65,-.84,;91.88,.49,;92.35,1.96,;91.32,3.1,;89.82,2.78,;89.34,1.31,;90.37,.17,;90.21,-4.44,;90.21,-5.98,;91.55,-3.67,;92.88,-4.45,;92.88,-5.98,;94.22,-6.75,;94.22,-8.28,;95.56,-5.98,;94.22,-3.67,;94.22,-2.13,;95.55,-4.44,;96.88,-3.67,;96.88,-2.12,;98.22,-1.36,;95.55,-1.35,;98.22,-4.44,;98.22,-5.97,;99.56,-3.67,;100.88,-4.43,;100.88,-5.97,;102.22,-6.74,;102.22,-8.28,;103.56,-9.05,;103.56,-10.58,;102.22,-3.66,;102.22,-2.12,;103.56,-4.43,;104.88,-3.66,;106.22,-4.43,;106.22,-5.97,;107.56,-3.66,;108.88,-4.42,;108.88,-5.96,;110.23,-6.73,;110.23,-8.27,;111.56,-9.04,;111.56,-10.58,;110.23,-11.34,;112.9,-11.35,;110.23,-3.65,;111.55,-4.42,;110.23,-2.11,)|
Show InChI InChI=1S/C151H228N42O47/c1-14-76(6)121(148(238)185-103(59-84-30-17-15-18-31-84)138(228)171-80(10)128(218)181-106(62-87-65-163-92-35-22-21-34-90(87)92)140(230)182-102(58-74(2)3)142(232)191-120(75(4)5)147(237)180-94(36-23-26-54-152)130(220)164-67-113(203)172-93(124(157)214)39-29-57-162-151(158)159)192-137(227)101(48-53-118(210)211)178-134(224)95(37-24-27-55-153)174-126(216)78(8)168-125(215)77(7)170-133(223)99(44-49-111(155)201)173-114(204)68-165-132(222)98(47-52-117(208)209)177-136(226)100(45-50-112(156)202)179-139(229)104(61-86-40-42-89(200)43-41-86)183-144(234)108(70-194)188-146(236)109(71-195)187-135(225)96(38-25-28-56-161-83(13)199)176-141(231)107(64-119(212)213)184-145(235)110(72-196)189-150(240)123(82(12)198)193-143(233)105(60-85-32-19-16-20-33-85)186-149(239)122(81(11)197)190-115(205)69-166-131(221)97(46-51-116(206)207)175-127(217)79(9)169-129(219)91(154)63-88-66-160-73-167-88/h15-22,30-35,40-43,65-66,73-82,91,93-110,120-123,163,194-198,200H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,201)(H2,156,202)(H2,157,214)(H,160,167)(H,161,199)(H,164,220)(H,165,222)(H,166,221)(H,168,215)(H,169,219)(H,170,223)(H,171,228)(H,172,203)(H,173,204)(H,174,216)(H,175,217)(H,176,231)(H,177,226)(H,178,224)(H,179,229)(H,180,237)(H,181,218)(H,182,230)(H,183,234)(H,184,235)(H,185,238)(H,186,239)(H,187,225)(H,188,236)(H,189,240)(H,190,205)(H,191,232)(H,192,227)(H,193,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,158,159,162)/t76-,77-,78-,79-,80-,81+,82+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 0.0120n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression

Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))		BDBM50273758
PNG
((4S,7S,10S,13S,16S,22S,25S,28S,31S,34S,37S,40S,43S...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O |r,wU:154.156,140.147,132.134,162.166,117.118,165.169,103.108,85.88,67.76,49.54,36.41,26.26,8.13,2.2,171.173,187.190,209.214,wD:149.151,121.130,111.114,91.100,79.82,58.63,31.31,17.22,4.4,182.186,201.206,216.221,229.234,(75.54,-8.31,;75.54,-6.76,;76.88,-6,;78.21,-6.77,;76.88,-4.46,;75.54,-3.7,;74.21,-4.47,;74.21,-6,;72.88,-3.69,;72.88,-2.15,;74.21,-1.38,;74.21,.16,;72.87,.93,;75.54,.92,;71.54,-4.47,;70.21,-3.7,;70.21,-2.16,;68.87,-4.47,;68.87,-6.01,;70.21,-6.78,;70.21,-8.31,;71.54,-9.09,;71.54,-10.62,;67.54,-3.7,;66.21,-4.47,;66.21,-6.01,;64.88,-3.71,;64.88,-2.16,;63.54,-4.48,;62.21,-3.71,;62.21,-2.17,;60.87,-4.48,;60.87,-6.02,;59.54,-3.71,;58.2,-4.48,;58.2,-6.02,;56.87,-3.72,;56.87,-2.18,;58.2,-1.4,;58.2,.14,;56.86,.91,;59.54,.91,;55.54,-4.49,;54.21,-3.72,;54.21,-2.17,;52.86,-4.49,;51.54,-3.73,;50.2,-4.5,;50.2,-6.03,;48.87,-3.72,;48.87,-2.18,;50.2,-1.41,;50.2,.13,;48.86,.9,;51.54,.89,;47.54,-4.5,;46.2,-3.73,;46.2,-2.19,;44.87,-4.5,;44.87,-6.04,;46.2,-6.81,;46.2,-8.34,;44.87,-9.12,;47.54,-9.12,;43.53,-3.73,;42.2,-4.5,;42.2,-6.04,;40.87,-3.74,;40.87,-2.19,;42.2,-1.43,;43.53,-2.19,;44.86,-1.42,;44.86,.12,;46.2,.89,;43.52,.89,;42.2,.12,;39.53,-4.51,;38.2,-3.74,;38.2,-2.2,;36.87,-4.51,;36.87,-6.05,;38.2,-6.82,;35.53,-3.74,;34.19,-4.52,;34.19,-6.05,;32.87,-3.75,;32.87,-2.21,;34.19,-1.43,;31.53,-4.52,;30.2,-3.75,;30.2,-2.2,;28.86,-4.52,;28.86,-6.06,;30.2,-6.83,;30.2,-8.37,;31.53,-9.14,;31.53,-10.67,;30.2,-11.44,;30.2,-12.98,;28.87,-10.67,;27.53,-3.76,;26.2,-4.53,;26.2,-6.06,;24.86,-3.75,;24.86,-2.21,;26.2,-1.45,;27.52,-2.21,;26.2,.1,;23.52,-4.53,;22.2,-3.76,;22.2,-2.22,;20.86,-4.53,;20.86,-6.07,;22.2,-6.84,;19.52,-3.76,;18.19,-4.53,;18.19,-6.07,;16.86,-3.77,;15.52,-4.54,;14.19,-3.77,;14.19,-2.23,;12.85,-4.54,;12.85,-6.08,;14.19,-6.85,;15.52,-6.08,;16.86,-6.84,;16.86,-8.38,;15.53,-9.15,;14.2,-8.39,;11.53,-3.77,;10.19,-4.55,;10.19,-6.08,;8.85,-3.78,;7.52,-4.55,;6.19,-3.78,;6.19,-2.23,;4.85,-4.55,;3.53,-3.79,;2.18,-4.56,;2.18,-6.09,;.85,-3.78,;.85,-2.24,;2.18,-1.48,;2.18,.07,;.85,.84,;3.52,.83,;-.48,-4.56,;-1.81,-3.79,;-1.81,-2.25,;-3.15,-4.56,;-3.15,-6.1,;-4.48,-3.79,;-5.82,-4.57,;-5.82,-6.1,;-7.15,-3.79,;-8.49,-4.56,;-7.15,-2.25,;-5.82,-1.49,;-4.42,-2.11,;-3.38,-.97,;-4.15,.37,;-5.66,.05,;8.85,-2.24,;7.52,-1.46,;10.19,-1.46,;16.86,-2.22,;15.52,-1.45,;18.19,-1.46,;78.21,-3.69,;78.21,-2.14,;79.54,-4.46,;80.88,-3.69,;80.88,-2.15,;82.21,-1.37,;83.54,-2.14,;84.88,-1.37,;84.88,.17,;83.54,.93,;82.21,.16,;82.21,-4.45,;82.21,-5.99,;83.55,-3.68,;84.88,-4.45,;84.88,-5.99,;86.21,-3.68,;86.21,-2.14,;87.55,-4.45,;88.89,-3.68,;88.89,-2.14,;90.21,-1.37,;91.62,-1.99,;92.65,-.84,;91.88,.49,;92.35,1.96,;91.32,3.1,;89.82,2.78,;89.34,1.31,;90.37,.17,;90.21,-4.44,;90.21,-5.98,;91.55,-3.67,;92.88,-4.45,;92.88,-5.98,;94.22,-6.75,;94.22,-8.28,;95.56,-5.98,;94.22,-3.67,;94.22,-2.13,;95.55,-4.44,;96.88,-3.67,;96.88,-2.12,;98.22,-1.36,;95.55,-1.35,;98.22,-4.44,;98.22,-5.97,;99.56,-3.67,;100.88,-4.43,;100.88,-5.97,;102.22,-6.74,;102.22,-8.28,;103.56,-9.05,;103.56,-10.58,;102.22,-3.66,;102.22,-2.12,;103.56,-4.43,;104.88,-3.66,;106.22,-4.43,;106.22,-5.97,;107.56,-3.66,;108.88,-4.42,;108.88,-5.96,;110.23,-6.73,;110.23,-8.27,;111.56,-9.04,;111.56,-10.58,;110.23,-11.34,;112.9,-11.35,;110.23,-3.65,;111.55,-4.42,;110.23,-2.11,)|
Show InChI InChI=1S/C151H228N42O47/c1-14-76(6)121(148(238)185-103(59-84-30-17-15-18-31-84)138(228)171-80(10)128(218)181-106(62-87-65-163-92-35-22-21-34-90(87)92)140(230)182-102(58-74(2)3)142(232)191-120(75(4)5)147(237)180-94(36-23-26-54-152)130(220)164-67-113(203)172-93(124(157)214)39-29-57-162-151(158)159)192-137(227)101(48-53-118(210)211)178-134(224)95(37-24-27-55-153)174-126(216)78(8)168-125(215)77(7)170-133(223)99(44-49-111(155)201)173-114(204)68-165-132(222)98(47-52-117(208)209)177-136(226)100(45-50-112(156)202)179-139(229)104(61-86-40-42-89(200)43-41-86)183-144(234)108(70-194)188-146(236)109(71-195)187-135(225)96(38-25-28-56-161-83(13)199)176-141(231)107(64-119(212)213)184-145(235)110(72-196)189-150(240)123(82(12)198)193-143(233)105(60-85-32-19-16-20-33-85)186-149(239)122(81(11)197)190-115(205)69-166-131(221)97(46-51-116(206)207)175-127(217)79(9)169-129(219)91(154)63-88-66-160-73-167-88/h15-22,30-35,40-43,65-66,73-82,91,93-110,120-123,163,194-198,200H,14,23-29,36-39,44-64,67-72,152-154H2,1-13H3,(H2,155,201)(H2,156,202)(H2,157,214)(H,160,167)(H,161,199)(H,164,220)(H,165,222)(H,166,221)(H,168,215)(H,169,219)(H,170,223)(H,171,228)(H,172,203)(H,173,204)(H,174,216)(H,175,217)(H,176,231)(H,177,226)(H,178,224)(H,179,229)(H,180,237)(H,181,218)(H,182,230)(H,183,234)(H,184,235)(H,185,238)(H,186,239)(H,187,225)(H,188,236)(H,189,240)(H,190,205)(H,191,232)(H,192,227)(H,193,233)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,158,159,162)/t76-,77-,78-,79-,80-,81+,82+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,120-,121-,122-,123-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.60n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells

Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair