BDBM50274418 CHEMBL4126032

SMILES: CN(C1CCN(CCCN2CCCc3c(Oc4ccc(Cl)c(Cl)c4)nccc3C2=O)CC1)S(C)(=O)=O

InChI Key: InChIKey=QZWJYVORWDVGEE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50274418 (CHEMBL4126032) Show SMILES CN(C1CCN(CCCN2CCCc3c(Oc4ccc(Cl)c(Cl)c4)nccc3C2=O)CC1)S(C)(=O)=O Show InChI InChI=1S/C25H32Cl2N4O4S/c1-29(36(2,33)34)18-9-15-30(16-10-18)12-4-14-31-13-3-5-20-21(25(31)32)8-11-28-24(20)35-19-6-7-22(26)23(27)17-19/h6-8,11,17-18H,3-5,9-10,12-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...				Bioorg Med Chem 26: 3559-3572 (2018) Article DOI: 10.1016/j.bmc.2018.05.027 BindingDB Entry DOI: 10.7270/Q2H41TZH
					More data for this Ligand-Target Pair