BDBM50274492 CHEMBL4128975

SMILES: Clc1ccc(Nc2nccc3c2CCCN(CCCN2CCCCC2)C3=O)cc1Cl

InChI Key: InChIKey=CAYQKSJDIQFNIT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50274492 (CHEMBL4128975) Show SMILES Clc1ccc(Nc2nccc3c2CCCN(CCCN2CCCCC2)C3=O)cc1Cl Show InChI InChI=1S/C23H28Cl2N4O/c24-20-8-7-17(16-21(20)25)27-22-18-6-4-14-29(23(30)19(18)9-10-26-22)15-5-13-28-11-2-1-3-12-28/h7-10,16H,1-6,11-15H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...				Bioorg Med Chem 26: 3559-3572 (2018) Article DOI: 10.1016/j.bmc.2018.05.027 BindingDB Entry DOI: 10.7270/Q2H41TZH
					More data for this Ligand-Target Pair