BDBM50274944 CHEMBL458802::cis-4-[4-(2-Chlorophenyl)cyclohexyl]-1-(2-pyridinyl)piperazine

SMILES: Clc1ccccc1[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1

InChI Key: InChIKey=QSUQNNQRYGZRHL-HDICACEKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (Cavia porcellus)	BDBM50274944 (CHEMBL458802 | cis-4-[4-(2-Chlorophenyl)cyclohexyl...) Show SMILES Clc1ccccc1[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 |r,wU:7.7,10.14,(2.07,.71,;2.07,-.83,;.74,-1.6,;.74,-3.14,;2.07,-3.92,;3.41,-3.14,;3.41,-1.59,;4.74,-.81,;6.07,-1.58,;7.4,-.81,;7.4,.73,;6.06,1.5,;4.73,.72,;8.73,1.5,;10.06,.72,;11.39,1.48,;11.4,3.02,;10.06,3.8,;8.72,3.03,;12.73,3.79,;12.73,5.32,;14.06,6.09,;15.4,5.32,;15.39,3.77,;14.06,3.01,)| Show InChI InChI=1S/C21H26ClN3/c22-20-6-2-1-5-19(20)17-8-10-18(11-9-17)24-13-15-25(16-14-24)21-7-3-4-12-23-21/h1-7,12,17-18H,8-11,13-16H2/t17-,18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membrane				J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50274944 (CHEMBL458802 | cis-4-[4-(2-Chlorophenyl)cyclohexyl...) Show SMILES Clc1ccccc1[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 |r,wU:7.7,10.14,(2.07,.71,;2.07,-.83,;.74,-1.6,;.74,-3.14,;2.07,-3.92,;3.41,-3.14,;3.41,-1.59,;4.74,-.81,;6.07,-1.58,;7.4,-.81,;7.4,.73,;6.06,1.5,;4.73,.72,;8.73,1.5,;10.06,.72,;11.39,1.48,;11.4,3.02,;10.06,3.8,;8.72,3.03,;12.73,3.79,;12.73,5.32,;14.06,6.09,;15.4,5.32,;15.39,3.77,;14.06,3.01,)| Show InChI InChI=1S/C21H26ClN3/c22-20-6-2-1-5-19(20)17-8-10-18(11-9-17)24-13-15-25(16-14-24)21-7-3-4-12-23-21/h1-7,12,17-18H,8-11,13-16H2/t17-,18+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellum				J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3
					More data for this Ligand-Target Pair