BDBM50274970 CHEMBL513936::trans-4-[4-(2,6-Dimethoxyphenyl)cyclohexyl]-1-(2-pyridinyl)piperazine

SMILES: COc1cccc(OC)c1[C@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1

InChI Key: InChIKey=NYWPLIFCHQRPAI-WGSAOQKQSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (Cavia porcellus)	BDBM50274970 (CHEMBL513936 | trans-4-[4-(2,6-Dimethoxyphenyl)cyc...) Show SMILES COc1cccc(OC)c1[C@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 |r,wU:10.10,wD:13.17,(-7.45,-22.18,;-8.78,-22.95,;-8.77,-24.49,;-10.1,-25.26,;-10.1,-26.81,;-8.77,-27.58,;-7.43,-26.81,;-6.1,-27.57,;-6.1,-29.11,;-7.44,-25.26,;-6.11,-24.47,;-6.12,-22.94,;-4.78,-22.17,;-3.44,-22.94,;-3.45,-24.47,;-4.77,-25.24,;-2.12,-22.17,;-.78,-22.94,;.54,-22.18,;.55,-20.64,;-.78,-19.86,;-2.12,-20.63,;1.89,-19.87,;1.89,-18.34,;3.22,-17.57,;4.56,-18.35,;4.55,-19.89,;3.21,-20.65,)| Show InChI InChI=1S/C23H31N3O2/c1-27-20-6-5-7-21(28-2)23(20)18-9-11-19(12-10-18)25-14-16-26(17-15-25)22-8-3-4-13-24-22/h3-8,13,18-19H,9-12,14-17H2,1-2H3/t18-,19-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membrane				J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50274970 (CHEMBL513936 | trans-4-[4-(2,6-Dimethoxyphenyl)cyc...) Show SMILES COc1cccc(OC)c1[C@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 |r,wU:10.10,wD:13.17,(-7.45,-22.18,;-8.78,-22.95,;-8.77,-24.49,;-10.1,-25.26,;-10.1,-26.81,;-8.77,-27.58,;-7.43,-26.81,;-6.1,-27.57,;-6.1,-29.11,;-7.44,-25.26,;-6.11,-24.47,;-6.12,-22.94,;-4.78,-22.17,;-3.44,-22.94,;-3.45,-24.47,;-4.77,-25.24,;-2.12,-22.17,;-.78,-22.94,;.54,-22.18,;.55,-20.64,;-.78,-19.86,;-2.12,-20.63,;1.89,-19.87,;1.89,-18.34,;3.22,-17.57,;4.56,-18.35,;4.55,-19.89,;3.21,-20.65,)| Show InChI InChI=1S/C23H31N3O2/c1-27-20-6-5-7-21(28-2)23(20)18-9-11-19(12-10-18)25-14-16-26(17-15-25)22-8-3-4-13-24-22/h3-8,13,18-19H,9-12,14-17H2,1-2H3/t18-,19-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	215	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellum				J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3
					More data for this Ligand-Target Pair