BDBM50275346 5-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N2-(2-(pyridin-4-yl)ethyl)-N4-p-tolylpyrimidine-2,4-diamine::CHEMBL486948

SMILES: Cc1ccc(Nc2nc(NCCc3ccncc3)ncc2-c2nnc(o2)C2CC2)cc1

InChI Key: InChIKey=VIVVUXJMHUNAFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50275346 (5-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N2-(2-(pyri...) Show SMILES Cc1ccc(Nc2nc(NCCc3ccncc3)ncc2-c2nnc(o2)C2CC2)cc1 Show InChI InChI=1S/C23H23N7O/c1-15-2-6-18(7-3-15)27-20-19(22-30-29-21(31-22)17-4-5-17)14-26-23(28-20)25-13-10-16-8-11-24-12-9-16/h2-3,6-9,11-12,14,17H,4-5,10,13H2,1H3,(H2,25,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged FLT3 (unknown origin) by ELISA				Bioorg Med Chem Lett 18: 5472-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.031 BindingDB Entry DOI: 10.7270/Q2WD40DQ
					More data for this Ligand-Target Pair