BDBM50275543 CHEMBL4125736

SMILES: Cc1cnc(O[C@@H]2Cc3c(cnn3C2)-c2ccc(cc2C)C#N)nc1

InChI Key: InChIKey=NRWLGOYLVCHHOA-OAHLLOKOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM50275543 (CHEMBL4125736) Show SMILES Cc1cnc(O[C@@H]2Cc3c(cnn3C2)-c2ccc(cc2C)C#N)nc1 |r| Show InChI InChI=1S/C19H17N5O/c1-12-8-21-19(22-9-12)25-15-6-18-17(10-23-24(18)11-15)16-4-3-14(7-20)5-13(16)2/h3-5,8-10,15H,6,11H2,1-2H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in Chinese hamster V79 cells assessed as reduction in corticosterone production using deoxycorticosterone as su...				J Med Chem 61: 5594-5608 (2018) Article DOI: 10.1021/acs.jmedchem.8b00328 BindingDB Entry DOI: 10.7270/Q2F47RN9
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (Homo sapiens (Human))	BDBM50275543 (CHEMBL4125736) Show SMILES Cc1cnc(O[C@@H]2Cc3c(cnn3C2)-c2ccc(cc2C)C#N)nc1 |r| Show InChI InChI=1S/C19H17N5O/c1-12-8-21-19(22-9-12)25-15-6-18-17(10-23-24(18)11-15)16-4-3-14(7-20)5-13(16)2/h3-5,8-10,15H,6,11H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in Chinese hamster V79 cell mitochondria assessed as reduction in aldosterone production using deoxycorticoster...				J Med Chem 61: 5594-5608 (2018) Article DOI: 10.1021/acs.jmedchem.8b00328 BindingDB Entry DOI: 10.7270/Q2F47RN9
					More data for this Ligand-Target Pair