BDBM50275626 CHEMBL487977::N-(3-methoxyphenyl)-5-methyl-7-phenylimidazo[1,5-f][1,2,4]triazin-2-amine

SMILES: COc1cccc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)c1

InChI Key: InChIKey=JDTGPBOAWBXCCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50275626 (CHEMBL487977 | N-(3-methoxyphenyl)-5-methyl-7-phen...) Show SMILES COc1cccc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)c1 Show InChI InChI=1S/C19H17N5O/c1-13-17-12-20-19(22-15-9-6-10-16(11-15)25-2)23-24(17)18(21-13)14-7-4-3-5-8-14/h3-12H,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cells				Bioorg Med Chem Lett 18: 6214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.100 BindingDB Entry DOI: 10.7270/Q22Z15DQ
					More data for this Ligand-Target Pair