BDBM50275818 CHEMBL4129132
SMILES: COc1cc(cc(F)c1NS(C)(=O)=O)C(C)C(=O)NCc1ccc(nc1N1CCC(C)CC1)C(F)(F)F
InChI Key: InChIKey=MFSZKAHYIGZQBL-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50275818![]() (CHEMBL4129132) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Antagonist activity at recombinant human TRPV1 expressed in CHOK1 cells assessed as reduction in capsaicin-induced Ca2+ flux after 15 mins by fluo-4-... | Bioorg Med Chem Lett 28: 2539-2542 (2018) Article DOI: 10.1016/j.bmcl.2018.05.043 BindingDB Entry DOI: 10.7270/Q2MP55RX | |||||||||||
More data for this Ligand-Target Pair |