BDBM50276053 5-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N4-methyl-N2-(2-(pyridin-4-yl)ethyl)pyrimidine-2,4-diamine::CHEMBL471020

SMILES: CNc1nc(NCCc2ccncc2)ncc1-c1nnc(o1)C1CC1

InChI Key: InChIKey=UVQWMYZKDNUBPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50276053 (5-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N4-methyl-N...) Show SMILES CNc1nc(NCCc2ccncc2)ncc1-c1nnc(o1)C1CC1 Show InChI InChI=1S/C17H19N7O/c1-18-14-13(16-24-23-15(25-16)12-2-3-12)10-21-17(22-14)20-9-6-11-4-7-19-8-5-11/h4-5,7-8,10,12H,2-3,6,9H2,1H3,(H2,18,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged FLT3 (unknown origin) by ELISA				Bioorg Med Chem Lett 18: 5472-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.031 BindingDB Entry DOI: 10.7270/Q2WD40DQ
					More data for this Ligand-Target Pair