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BDBM50276183 CHEMBL4128937

SMILES: Cl.C[C@H]1CCCN1Cc1cc(ccc1-c1ccccc1)C(=O)Nc1ccc2CCC(=O)N(C)c2c1

InChI Key: InChIKey=AYNMAXVDLFXDJO-BDQAORGHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276183   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50276183
PNG
(CHEMBL4128937)
Show SMILES Cl.C[C@H]1CCCN1Cc1cc(ccc1-c1ccccc1)C(=O)Nc1ccc2CCC(=O)N(C)c2c1 |r|
Show InChI InChI=1S/C29H31N3O2.ClH/c1-20-7-6-16-32(20)19-24-17-23(11-14-26(24)21-8-4-3-5-9-21)29(34)30-25-13-10-22-12-15-28(33)31(2)27(22)18-25;/h3-5,8-11,13-14,17-18,20H,6-7,12,15-16,19H2,1-2H3,(H,30,34);1H/t20-;/m0./s1
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PC cid
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Article
PubMed
n/an/a 890n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]RTX from human TRPV1 expressed in HEK293 cell membranes after 60 mins by scintillation counting method


Bioorg Med Chem 26: 3716-3726 (2018)


Article DOI: 10.1016/j.bmc.2018.06.001
BindingDB Entry DOI: 10.7270/Q2FX7D0K
More data for this
Ligand-Target Pair