BDBM50276185 CHEMBL4126963

SMILES: OC(=O)C(O)=O.CN1CCCc2ccc(NC(=O)c3ccc(c(CN4CCCCC4)c3)-c3ccccc3)cc12

InChI Key: InChIKey=KKPDEQFGRKJUFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50276185 (CHEMBL4126963) Show SMILES OC(=O)C(O)=O.CN1CCCc2ccc(NC(=O)c3ccc(c(CN4CCCCC4)c3)-c3ccccc3)cc12 Show InChI InChI=1S/C29H33N3O/c1-31-16-8-11-23-12-14-26(20-28(23)31)30-29(33)24-13-15-27(22-9-4-2-5-10-22)25(19-24)21-32-17-6-3-7-18-32/h2,4-5,9-10,12-15,19-20H,3,6-8,11,16-18,21H2,1H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 expressed in HEK293 cell membranes after 60 mins by scintillation counting method				Bioorg Med Chem 26: 3716-3726 (2018) Article DOI: 10.1016/j.bmc.2018.06.001 BindingDB Entry DOI: 10.7270/Q2FX7D0K
					More data for this Ligand-Target Pair