BDBM50276193 CHEMBL4128465

SMILES: Cl.O=C(Nc1ccc2CCC(=O)Nc2c1)c1ccc(c(CN2CCCCC2)c1)-c1ccccc1

InChI Key: InChIKey=WBFCQBBITSNDBB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50276193 (CHEMBL4128465) Show SMILES Cl.O=C(Nc1ccc2CCC(=O)Nc2c1)c1ccc(c(CN2CCCCC2)c1)-c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c32-27-14-11-21-9-12-24(18-26(21)30-27)29-28(33)22-10-13-25(20-7-3-1-4-8-20)23(17-22)19-31-15-5-2-6-16-31/h1,3-4,7-10,12-13,17-18H,2,5-6,11,14-16,19H2,(H,29,33)(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 expressed in HEK293 cell membranes after 60 mins by scintillation counting method				Bioorg Med Chem 26: 3716-3726 (2018) Article DOI: 10.1016/j.bmc.2018.06.001 BindingDB Entry DOI: 10.7270/Q2FX7D0K
					More data for this Ligand-Target Pair