BDBM50276423 (2S,4S)-1-((2S,3S)-2-amino-3-methylpentanoyl)-4-fluoropyrrolidine-2-carbonitrile::CHEMBL461117

SMILES: CC[C@H](C)[C@H](N)C(=O)N1C[C@@H](F)C[C@H]1C#N

InChI Key: InChIKey=MJBNFAWLBDDEBY-XKNYDFJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50276423 ((2S,4S)-1-((2S,3S)-2-amino-3-methylpentanoyl)-4-fl...) Show SMILES CC[C@H](C)[C@H](N)C(=O)N1C[C@@H](F)C[C@H]1C#N |r| Show InChI InChI=1S/C11H18FN3O/c1-3-7(2)10(14)11(16)15-6-8(12)4-9(15)5-13/h7-10H,3-4,6,14H2,1-2H3/t7-,8-,9-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Matrix Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem 17: 1783-802 (2009) Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ
					More data for this Ligand-Target Pair