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SMILES: CCN(C1CCN(CC1)C(C)C[C@H](NC(=O)C1CCC1)c1ccccc1)C(=O)c1ccccc1

InChI Key: InChIKey=SJAHKAVMZZYMHY-ZUILJJEPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276807   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50276807
PNG
(CHEMBL460008 | N-(1-((4S)-4-(cyclobutanecarboxamid...)
Show SMILES CCN(C1CCN(CC1)C(C)C[C@H](NC(=O)C1CCC1)c1ccccc1)C(=O)c1ccccc1 |r|
Show InChI InChI=1S/C29H39N3O2/c1-3-32(29(34)25-13-8-5-9-14-25)26-17-19-31(20-18-26)22(2)21-27(23-11-6-4-7-12-23)30-28(33)24-15-10-16-24/h4-9,11-14,22,24,26-27H,3,10,15-21H2,1-2H3,(H,30,33)/t22?,27-/m0/s1
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PC sid
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Similars
Article
PubMed
n/an/a 73.5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...

Bioorg Med Chem Lett 19: 1075-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.009
BindingDB Entry DOI: 10.7270/Q27M08VH
More data for this
Ligand-Target Pair