BDBM50276808 CHEMBL460009::N-((1S)-3-(4-(2-oxo-4-phenyl-2,3-dihydro-1H-imidazol-1-yl)piperidin-1-yl)-1-phenylbutyl)cyclobutanecarboxamide

SMILES: CC(C[C@H](NC(=O)C1CCC1)c1ccccc1)N1CCC(CC1)n1cc([nH]c1=O)-c1ccccc1

InChI Key: InChIKey=YUQVDSNVEXLLAE-UQTORGHUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50276808 (CHEMBL460009 | N-((1S)-3-(4-(2-oxo-4-phenyl-2,3-di...) Show SMILES CC(C[C@H](NC(=O)C1CCC1)c1ccccc1)N1CCC(CC1)n1cc([nH]c1=O)-c1ccccc1 |r| Show InChI InChI=1S/C29H36N4O2/c1-21(19-26(22-9-4-2-5-10-22)30-28(34)24-13-8-14-24)32-17-15-25(16-18-32)33-20-27(31-29(33)35)23-11-6-3-7-12-23/h2-7,9-12,20-21,24-26H,8,13-19H2,1H3,(H,30,34)(H,31,35)/t21?,26-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...				Bioorg Med Chem Lett 19: 1075-9 (2009) Article DOI: 10.1016/j.bmcl.2009.01.009 BindingDB Entry DOI: 10.7270/Q27M08VH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50276808 (CHEMBL460009 | N-((1S)-3-(4-(2-oxo-4-phenyl-2,3-di...) Show SMILES CC(C[C@H](NC(=O)C1CCC1)c1ccccc1)N1CCC(CC1)n1cc([nH]c1=O)-c1ccccc1 |r| Show InChI InChI=1S/C29H36N4O2/c1-21(19-26(22-9-4-2-5-10-22)30-28(34)24-13-8-14-24)32-17-15-25(16-18-32)33-20-27(31-29(33)35)23-11-6-3-7-12-23/h2-7,9-12,20-21,24-26H,8,13-19H2,1H3,(H,30,34)(H,31,35)/t21?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 19: 1075-9 (2009) Article DOI: 10.1016/j.bmcl.2009.01.009 BindingDB Entry DOI: 10.7270/Q27M08VH
					More data for this Ligand-Target Pair