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SMILES: CC(C[C@H](NC(=O)C1CCC1)c1ccccc1)N1CCC(CC1)c1nnc(C)o1

InChI Key: InChIKey=QLGQRXYOSUSUDN-MRNPHLECSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276896   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50276896
PNG
(CHEMBL516939 | N-((1S)-3-(4-(5-methyl-1,3,4-oxadia...)
Show SMILES CC(C[C@H](NC(=O)C1CCC1)c1ccccc1)N1CCC(CC1)c1nnc(C)o1 |r|
Show InChI InChI=1S/C23H32N4O2/c1-16(27-13-11-20(12-14-27)23-26-25-17(2)29-23)15-21(18-7-4-3-5-8-18)24-22(28)19-9-6-10-19/h3-5,7-8,16,19-21H,6,9-15H2,1-2H3,(H,24,28)/t16?,21-/m0/s1
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Similars
Article
PubMed
n/an/a 1.85E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...

Bioorg Med Chem Lett 19: 1075-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.009
BindingDB Entry DOI: 10.7270/Q27M08VH
More data for this
Ligand-Target Pair