BDBM50276897 CHEMBL459599::N-((1S)-3-(4-(3-methyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-1-phenylbutyl)cyclobutanecarboxamide

SMILES: CC(C[C@H](NC(=O)C1CCC1)c1ccccc1)N1CCC(CC1)c1nc(C)no1

InChI Key: InChIKey=OFVRZICHCGTOPE-MRNPHLECSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50276897 (CHEMBL459599 | N-((1S)-3-(4-(3-methyl-1,2,4-oxadia...) Show SMILES CC(C[C@H](NC(=O)C1CCC1)c1ccccc1)N1CCC(CC1)c1nc(C)no1 |r| Show InChI InChI=1S/C23H32N4O2/c1-16(27-13-11-20(12-14-27)23-24-17(2)26-29-23)15-21(18-7-4-3-5-8-18)25-22(28)19-9-6-10-19/h3-5,7-8,16,19-21H,6,9-15H2,1-2H3,(H,25,28)/t16?,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...				Bioorg Med Chem Lett 19: 1075-9 (2009) Article DOI: 10.1016/j.bmcl.2009.01.009 BindingDB Entry DOI: 10.7270/Q27M08VH
					More data for this Ligand-Target Pair