null

SMILES: Clc1ccc(Cl)c(c1)S(=O)(=O)c1cccc2oc(nc12)N1CCNCC1

InChI Key: InChIKey=LVODYRRCDSJHFP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50277016 (4-(2,5-dichlorophenylsulfonyl)-2-(piperazin-1-yl)b...) Show SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)c1cccc2oc(nc12)N1CCNCC1 Show InChI InChI=1S/C17H15Cl2N3O3S/c18-11-4-5-12(19)15(10-11)26(23,24)14-3-1-2-13-16(14)21-17(25-13)22-8-6-20-7-9-22/h1-5,10,20H,6-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 1115-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.107 BindingDB Entry DOI: 10.7270/Q2X066WD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50277016 (4-(2,5-dichlorophenylsulfonyl)-2-(piperazin-1-yl)b...) Show SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)c1cccc2oc(nc12)N1CCNCC1 Show InChI InChI=1S/C17H15Cl2N3O3S/c18-11-4-5-12(19)15(10-11)26(23,24)14-3-1-2-13-16(14)21-17(25-13)22-8-6-20-7-9-22/h1-5,10,20H,6-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5HT-stimulated cAMP formation after 10 mins b...				Bioorg Med Chem Lett 19: 1115-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.107 BindingDB Entry DOI: 10.7270/Q2X066WD
					More data for this Ligand-Target Pair