BDBM50277040 4-(6-(4-chlorophenyl)-2,6-diazabicyclo[2.2.1]heptan-2-yl)-1-(4-fluorophenyl)butan-1-one::CHEMBL514591

SMILES: Fc1ccc(cc1)C(=O)CCCN1CC2CC1N(C2)c1ccc(Cl)cc1

InChI Key: InChIKey=ZBMQPMVISGXIDJ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50277040 (4-(6-(4-chlorophenyl)-2,6-diazabicyclo[2.2.1]hepta...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CC2CC1N(C2)c1ccc(Cl)cc1 |TLB:11:12:17.18:15,THB:19:17:15:12.13| Show InChI InChI=1S/C21H22ClFN2O/c22-17-5-9-19(10-6-17)25-14-15-12-21(25)24(13-15)11-1-2-20(26)16-3-7-18(23)8-4-16/h3-10,15,21H,1-2,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50277040 (4-(6-(4-chlorophenyl)-2,6-diazabicyclo[2.2.1]hepta...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CC2CC1N(C2)c1ccc(Cl)cc1 |TLB:11:12:17.18:15,THB:19:17:15:12.13| Show InChI InChI=1S/C21H22ClFN2O/c22-17-5-9-19(10-6-17)25-14-15-12-21(25)24(13-15)11-1-2-20(26)16-3-7-18(23)8-4-16/h3-10,15,21H,1-2,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50277040 (4-(6-(4-chlorophenyl)-2,6-diazabicyclo[2.2.1]hepta...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CC2CC1N(C2)c1ccc(Cl)cc1 |TLB:11:12:17.18:15,THB:19:17:15:12.13| Show InChI InChI=1S/C21H22ClFN2O/c22-17-5-9-19(10-6-17)25-14-15-12-21(25)24(13-15)11-1-2-20(26)16-3-7-18(23)8-4-16/h3-10,15,21H,1-2,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	513	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair