BDBM50277740 4-Deoxy-4alpha-Phorbol 12,13-didecanoate::CHEMBL504854

SMILES: CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@H]3CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCCCCCCCC

InChI Key: InChIKey=UPYTZZZLHBKNFL-KVUNZBAESA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Mus musculus)	BDBM50277740 (4-Deoxy-4alpha-Phorbol 12,13-didecanoate | CHEMBL5...) Show SMILES CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@H]3CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCCCCCCCC |r,c:28,t:18| Show InChI InChI=1S/C40H64O7/c1-7-9-11-13-15-17-19-21-33(42)46-37-28(4)39(45)31-23-27(3)35(44)30(31)24-29(26-41)25-32(39)36-38(5,6)40(36,37)47-34(43)22-20-18-16-14-12-10-8-2/h23,25,28,30-32,36-37,41,45H,7-22,24,26H2,1-6H3/t28-,30-,31-,32+,36?,37-,39+,40-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration				J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3
					More data for this Ligand-Target Pair