BDBM50278144 1-(4-fluorophenyl)-4-(2-methoxybenzylidene)pyrazolidine-3,5-dione::CHEMBL470817

SMILES: COc1ccccc1C=C1C(=O)NN(C1=O)c1ccc(F)cc1

InChI Key: InChIKey=YPZXIVBOAZUHKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50278144 (1-(4-fluorophenyl)-4-(2-methoxybenzylidene)pyrazol...) Show SMILES COc1ccccc1C=C1C(=O)NN(C1=O)c1ccc(F)cc1 |w:8.8| Show InChI InChI=1S/C17H13FN2O3/c1-23-15-5-3-2-4-11(15)10-14-16(21)19-20(17(14)22)13-8-6-12(18)7-9-13/h2-10H,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Inje University Curated by ChEMBL					Assay Description Inhibition of Dyrk1 (unknown origin) autophosphorylation				Bioorg Med Chem Lett 19: 2324-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.062 BindingDB Entry DOI: 10.7270/Q2SN08VT
					More data for this Ligand-Target Pair